Background: As a novel non-apoptotic cell death, ferroptosis has been reported to play a crucial role in acute kidney injury (AKI), especially cisplatin-induced AKI.Valproic acid (VPA), an inhibitor of histone sara stedy price deacetylase (HDAC) 1 and 2, is used as an antiepileptic drug.Consistent with our data, a few studies have demonstrated that
Autophagy in the eye: from physiology to pathophysiology
Autophagy is a catabolic self-degradative pathway that promotes the degradation and recycling of intracellular material through the lysosomal compartment.Although first believed to function in conditions of nutritional stress, autophagy is emerging as a critical cellular pathway, involved bostik universal primer pro in a variety of physiological an